Obstructive Uropathy

Question 1

What are 3 common locations of obstruction?

Answer 1

• Ureto-pelvic junction
• Ureter crossing over iliac vessels
• Ureter meeting the bladder

Question 2

What is the MOST common location of obstruction?

Answer 2

Ureter meeting the bladder AKA the ureto-vesicular junction

Question 3

What drug can cause renal papilla necrosis and lead to obstruction?

Answer 3

Phenacetin

Question 4

What is a common cause of obstruction in pediatric patients?

Answer 4

Ureto-pelvic junction intramural obstruction

Question 5

Urethral Stricture Disease

Answer 5

Due to scarring often from STDs like gonorrhea/chlamydia

Question 6

Hydronephrosis

Answer 6

Dilation of pelvis and calyces of the kidney - not always due to obstruction

Question 7

Postobstructive Diuresis

Answer 7

Marked polyuria can be seen after relief of BUO or obstruction of a solitary kidney

Question 8

What are some possible cures of post obstructive diuresis?

Answer 8

• downregulation of sodium transporters
• loss of medullary interstitial solute gradient
• poor response to ADH