Oncogenes Flashcards by Peter Chamberlin

Q

BCR-ABL

A

CML/ALL

TK

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Q

bcl-2

A

Follicular and undifferentiated lymphomas

Anti-apoptotic

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Q

BRAF

A

Melanoma

Serine/Threonine Kinase

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Q

c-KIT

A

Gastrointestinal Stromal Tumor

Cytokine receptor (for stem cell factor)

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Q

c-myc

A

Burkitt lymphoma

Transcription Factor

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Q

HER2/neu

A

Breast, ovarian, and gastric carcinoma

Tyrosine kinase

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Q

L-myc

A

Lung cancer

TF

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Q

N-myc

A

Neuroblastoma

TF

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Q

ras

A

Colon cancer, lung cancer, pancreatic cancer

GTPase

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Q

ret

A

MEN 2A/2B

Tyrosine kinase

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