Oncology

Question 1

What is CDH1 mutation and treatment?

Answer 1

E-cadherin mutation, hereditary diffuse gastric cancer, prophylactic total gastrectomy between 18-30 yo, screen for breast cancer same as BRCA1/2

Question 2

What are the stages of non-hodgkin lymphoma?

Answer 2

I: one node or adjacent nodes

II: 2 or more nodal groups on same side of diaphragm
III: Nodes on both sides of diaphragm or supradiaphragmatic + splenic nodes
IV: diffuse involvement