Opioid

Question 1

List 6 opioid

Answer 1

Morphine
Methadone
Fentanyl
Pethidine
Codeine (dihydrocodeine)
Tramadol

Question 2

DDI between tramadol and ___?

Answer 2

Ondansetron: pain will come back if u take both tgt
Ondansetron: reduce vomitting

Question 3

SE of the opioid

Answer 3

1. common and mild: N/V/C, urinary retention
2. miosis (except pethidine)
3. drowsiness (except pethidine will cause hallucination, convulsant, restlessness)
4. postural hypotension, bradycardia
5. immunosuppressant
6. dependence (withdrawal sx), addiction and tolerance –> risk of overdose
7. overdose: severe sedation, resp depression

Question 4

morphine additional SE

Answer 4

urticaria, itching, bronchoconstriction, hypotension

Question 5

what is the drug that counteract opioid overdose

Answer 5

NALoxone
NALtrexone
NALmefene
Extreme caution in pt with opiate dependency as it can ppt fatal withdrawal sx

Question 6

withdrawal sx of opioid

Answer 6

anxiety, irritability
chill
hot flush
joint pain, 
tears, runny nose
N/V/D/ cramp