Opioid Dependence

Question 1

Buprenorphine (Subutex)

Answer 1

A) Partial Opioid Agonist

B)

1. Maintenance of Opioid Dependence (Subutex and Suboxone - contains naloxone)
2. Opioid Withdrawal
3. Mod. to Severe Pain (Temgesic and Norspan)

C)
Buprenorphine maintenance:
2-32mg daily

Opioid withdrawal
-tailored according to severety of withdrawal

Mod. to Severe Pain
200-400 microg every 6-8 hrs

D)
1. HEPATIC** (reduced elimination in impairment)
2.