Opioid misuse

Question 1

What kind of opioid misuse patients benefit from a programme of detoxification?

Answer 1

• Short history of misuse
• Uncomplicated history
• Relatively socially stable

Question 2

What kind of opioid misuse patients benefit from opiate blockade

Answer 2

Impulsive relapsers

Question 3

What non opioid drug is used in those detoxifying from opioids to alleviate some of the symptoms?

Answer 3

Lofexidine (alpha 2 adrenergic agonist)

Question 4

How do you start, then adjust, lofexidine use in opioid withdrawal?

Answer 4

Initial test dose
Maximise dose to overcome symptoms
Tailor down dose

Question 5

What two drugs are used as opioid substitution therapies?

Answer 5

Methadone

Buprenorphine

Question 6

How do you take buprenorphine?

Answer 6

Sublingual tablet

Question 7

What drug is added to naloxone to make it less likely to be misused in the community?

Answer 7

Naloxone