What is the mechanism of action of opioid analgesics?
They bind to mu-opioid receptors in the spinal cord(decrease perception of pain) and limbic system(modify reaction to pain)
Are opioids antipyretic or anti-inflammatory?
No
Uses for opioids?
Moderate to severe pain
adverse reactions to opioids?
Respiratory depression Sedation N/V Constipation Histamine release Urinary retention Tolerance -> dependence
Treatment of opioid OD?
Naloxone
List some Opioid analgesics.
Hydrocodone Oxycodone Codeine Fentanyl Morphine Hydromorphone Methadone Meperidine Tramadol
What opioid analgesics come with acetaminophen?
Hydrocodone, oxycodone, and codeine
If someone has already had PrEP, what is the PEP protocol?
2 doses of Rabies Vaccine (day 0 & 3)
No HBIg