S/S of 15% fluid defecit
Mucous Membranes---Parched Sensorium---Obtunded Orthostatic changes---HR >15 bpm, BP >10mmHg Urinary Flow---Marked decrease Pulse rate--->120bpm BP---decreased
Fluid maintenance requirement
4ml/kg/hr for first 10kg
2ml/kg/hr for next 10kg
1ml/kg/hr over 20kg
How to calculate preexisting fluid deficit
Multiply normal fluid maintenance by the length of fast (NPO,etc)
Factors associated with increased evaporative loss
Losses are proportionate to
Sources of information used when estimating blood loss
Calculate how much crystalloid and colloid should be used to replace a given amount of blood loss
3-4ml crystalloid per ml blood loss
1ml colloid/blood per ml blood loss
Crystalloid most commonly used in OR for fluids replacement
LR
Crystalloid most commonly used for RF pts and blood administration
NS–lowest pH of all commonly used crystalloids
Comorbidities which indicate an early use of colloid instead of crystalloid
Other uses-bacteremia,RI,trauma
Advantages of using hespan instead of albumin
Can use up to 1000ml
disadvantages of hespan instead of albumin
- -high doses assoc with dilutional thrombocytopenia, Renal Insufficiency
Negatives to colloid/albumin
Compare HCT of cell saver blood to blood bank
cells are washed (PCV 50-60%)
Clinical situations that preclude the use of cell saver
- -sepsis of operative site
HCT that indicates possible transfusion
21-24%
Methods of measuring HCT
What is the anticoagulant used in blood bank and a consideration with transfusion?
CPDA-1(citrate phosphate dextrose adenine)
binds Ca-watch levels
What is the appropriate storage temp of blood bank and how long does it last?
1-6 degrees Celsius
35 days
PLT count during surgery which indicates transfusion
<50,000 –assoc with increased blood loss during surgery
What medications are used to pretreat PLT infusion?
H1 gastric (reglan) H2 antagonist (antihistamine)
Steroids
Indications for FFP administration
-isolated factor deficiencies
-reversal of coumadin therapy
-coronary artery bypass
-correction of coagulopathy associated with
liver disease
Potential complications of massive transfusion
Lab test which may indicate hypovolemia
SCOM(ladig)
Suction, Stethoscope
Circuit
Oxygen
Monitor