A Advanced Principles A (Spring 2024) > Orthopedic Anesthesia > Flashcards

Orthopedic Anesthesia Flashcards

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1
Q

What are the two biggest factors associated with development of osteoporosis?

A
  • Elderly age
  • Menopause
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2
Q

What hormonal changes are characteristic of osteoporosis?

A
  • ↑ PTH
  • ↓ Vit D
  • ↓ HGH
  • ↓ Insulin-like growth factors
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3
Q

What are the four most common meds used to treat osteoporosis?

A

dronate drugs
- Fosamax (Alendronate)
- Actonel (Risedronate)
- Boniva (Ibandronic Acid)
- Reclast (Zoledronate)

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4
Q

Differentiate between Bouchard’s nodes and Heberden’s nodes.

A
  • Bouchard’s = proximal interphalangeal joints
  • Heberden’s = distal interphalangeal joints
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5
Q

What drug is the most common chondroprotective agent that helps protect the articular joint?

A

Glucosamine

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6
Q

What anesthetic considerations should be given to glucosamine?

A

Glucosamine needs to be stopped two weeks prior to surgery due to PLT aggregation inhibition.

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7
Q

Arthritis characterized by morning stiffness that improves throughout the day is….

A

Rheumatoid arthritis

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8
Q

Arthritis that is characterized by worsening symptoms throughout the course of the day is…

A

Osteoarthritis

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9
Q

What labs are typically elevated in a patient with rheumatoid arthritis?

A
  • ↑ Rheumatoid factor (RF)
  • ↑ Anti-immunoglobulin antibody
  • ↑ C-reactive protein (CRP)
  • ↑ Erythrocyte Sedimentation Rate (ESR)
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10
Q

What common dose of stress dose glucocorticoid is used for RA patients?

A

50mg hydrocortisone (Solu-cortef)

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11
Q

What two TNFα inhibitors are commonly used to treat RA?

A
  • Infliximab
  • Etanercept
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12
Q

Which of the following drugs treat RA?
- Methotrexate
- Hydroxychloroquine
- Sulfasalazine
- Leflunomide

A

Trick question. All of them do
- Methotrexate
- Hydroxychloroquine
- Sulfasalazine
- Leflunomide

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13
Q

What airway concerns should be considered with RA patients?

A
  • Limited TMJ movement
  • Narrowed glottic opening
  • Cricoarytenoid arthritis
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14
Q

Where is the most instability typically located in the cervical spine of RA patients?

A

Atlantoaxial Junction

(be careful not to displace the odontoid process and impinge on the c-spine or vertebral arteries)

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15
Q

What are the signs and symptoms of atlantoaxial subluxation?

A
  • Headache
  • Neck pain
  • Extremity paresthesias (especially with movement)
  • Bowel/bladder dysfunction
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16
Q

What are the signs/symptoms of vertebral artery occlusion?

A
  • N/V
  • Dysphagia
  • Blurred Vision
  • Transient LOC changes
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17
Q

What ocular syndrome is typical of RA patients?

A

Sjogren’s syndrome

(Dry eyes and mouth)

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18
Q

What pulmonary issues are associated with RA?

A
  • Interstitial fibrosis
  • Restricted ventilation
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19
Q

What type of ventilatory settings would be utilized for an RA patient exhibiting a restrictive ventilatory pattern?

A

Pressure Control @ 5mL/kg

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20
Q

What artery is typically injured due to pelvic fractures? Where is the bleeding located in this instance?

A

Iliac artery → retroperitoneal space bleeding

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21
Q

What is the typical worst complication of long bone fractures?

A

Bone marrow fat embolism

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22
Q

What technique is used for intubation of a patient who has c-spine concerns?

A

MILS

Manual In-Line Stabilization

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23
Q

Describe the MILS technique

A
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24
Q

What is the mechanism of action of warfarin?

A

Warfarin inhibits Vitamin K epoxide reductase and limits the availability of Vitamin K throughout the body

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25
What is the mechanism of action of LMWH?
LMWH binds to antithrombin thus → no thrombin → no fibrinogen forming into fibrin
26
What are some typical triggers for delirium?
- Hypoxemia - Hypotension - Hypercarbia - Sleep Deprivation - Hypervolemia - Infection - Electrolyte abnormalities - Pain - Benzos - Anticholinergics - Circadian Rhythm disruption
27
FEV₁ decreases by ___% for each decade of life.
10%
28
What occurs with closing volume as we age?
Closing volume **increases**.
29
What is the goal of regional anesthesia vs general anesthesia?
Avoid: - DVT - PE - EBL - Respiratory complications - Death
30
With placement of what device is fat embolism syndrome most likely to occur?
Femoral Medullary Canal Rod
31
What is the s/s Triad of fat embolism syndrome? When do s/s typically present?
1. Dyspnea 2. Confusion 3. Petechiae Typically presents in 12 - 72 hrs
32
What lab findings are noted with fat embolism syndrome?
- Fat macroglobulinemia - Anemia - Thrombocytopenia - ↑ ESR
33
What is ESR? What are normal values for males and females?
- Erythrocyte Sedimentation Rate - Male: 0 - 22 mm/hr - Female: 0 - 29 mm/hr
34
What minor s/s can be construed to characterize fat embolization syndrome?
- Fever - ↑HR - Jaundice - Renal Changes
35
What are the anesthetic management techniques for fat embolization syndrome?
Supportive Therapy - 100% FiO₂ - **No N₂O** - IV Heparin - CV & Resp support
36
What factors contribute to the development of DVT's?
- **Lack of Prophylaxis** - Obesity - > 60yrs old - > 30min procedure - Tourniquet use - > 4 days immobilization - > Lower extremity fracture
37
Which three surgery types present the greatest risk for DVT formation?
- Hip surgery - TKA - Lower extremity trauma
38
When does LMWH need to be initiated?
12 hours preop or 12 hours postop
39
Can neuraxial anesthesia be done after LMWH has been given?
Yes, if **10 - 12 hours** after the dose. *Delay next dose 4 hours*.
40
Can an epidural be placed in a patient on LMWH anticoagulation therapy?
No. No indwelling catheters
41
Neuraxial catheters must be removed ___ hours before the intiation of LMWH therapy.
2 hours
42
Can a patient have neuraxial anesthesia if on warfarin?
Only if the **INR is ≤ 1.5**
43
Flip card for Anticoagulation guidelines for Neuraxial procedures.
44
Flip card for additional Anticoagulation guidelines for Neuraxial procedures.
45
What advantages does neuraxial anesthesia present in the prevention of DVT's?
- ↑ extremity venous blood flow (sympathectomy). - LA systemic anti-inflammatory properties. - ↓ PLT reactivity
46
What is the maximum dose of TXA? (Tranexamic Acid)
2.5 g
47
What is typical dosing of TXA?
10 - 30 mg/kg **1000mg is typical**
48
Tourniquet pain typically begins ___ minutes after application.
45 min
49
The width of a tourniquet must be greater than ____ its diameter.
½
50
How long can tourniquets be placed on an extremity?
- 2 hours is typically not exceeded - **3 hours is max**.
51
What mmHg is typically used for thigh tourniquets?
300 mmHg (or 100 mmHg > SBP)
52
What mmHg is typically used for arm tourniquets?
250 mmHg (or 50 mmHg > SBP)
53
When utilizing a double tourniquet, it is important to remember to...
inflate proximal → deflate distal
54
What occurs with tourniquet deflation?
- Transient lactic acidosis - Transient Hypercarbia (thus V̇T) - ↑ HR - ↓ pain - ↓ CVP, BP, & temp
55
What are some important points of assessment necessary for upper body procedures preoperatively?
- Baseline vitals - Airway - Pre-existing nerve conduction issues - Examine pupils
56
What are the cardiac consequences of sitting/Beach Chair position?
- ↓ CO & BP - ↑ HR & SVR Due to pooling of blood in lower body.
57
What are the respiratory consequences of sitting/Beach Chair position?
- ↑ FRC & lung volumes
58
What are the neurologic consequences of sitting/Beach Chair position?
↓ CBF
59
How is venous air embolism prevented in a beach chair patient?
↑ CVP (above 0) to prevent a "suction" effect
60
In what percent of the population is a patent foramen ovale present?
20 - 30 %
61
How does one treat venous air embolism? *Besides prevention...*
- Inform surgeon → irrigation & occlusive dressing - DC N₂O if being used - Bilateral compression of jugular veins (prevent neuro consequences) - Place patient in head down position to trap in right atrium - Withdraw air through right atrial catheter - CV & Resp support
62
The ultrasound transducer is being utilized to located venous air embolism in a patient. Where do you place the probe?
2ⁿᵈ - 3rd ICS right of sternum *Over the Right Atrium*
63
Though ultrasound over the right atrium is the most sensitive indicator of VAE (venous air embolism), the most definitive is....
TEE
64
The characteristic sound of a VAE is a _____________ murmur.
"Mill-Wheel" murmur
65
What would be an indicator of a sudden decreased perfusion to the lungs?
↓ EtCO₂
66
________ of the neck in a sitting position patient can accidentally extubate them.
Hyperextension
67
In a sitting position patient, where would one zero their art line?
Tragus of the ear *Establishes knowledge of brain BP & thus perfusion*.
68
What are ocular conditions do we want to avoid due to the hypotension inherent to the sitting position?
- Retinal Ischemia - Ischemia Optic Neuropathy *Also avoid corneal abrasion*.
69
There is a 40cm distance from the patients heart to their brain. The patient's BP measured on the arm is 120/70. What is the estimated BP in the brain?
40cm x 0.77mmHg = 30.8mmHg 120 - 30.8 = 89.2mmHg 70 - 30.8 = 39.2mmHg The patient's brain BP is **89/39** Thus indicating hypotension and necessary correction.
70
A standing patient's NIBP on the arm is 134/92. The distance between the patient's knee and the NIBP cuff is 120cm. What is the BP in the patient's knee?
120 x 0.77 = 92.4 134 + 92 92 + 92 Patient's "knee" BP standing up is 226/184
71
What is the Bezold-Jarisch reflex?
Cardiac inhibitory reflex resulting in signification HoTN & ↓HR.
72
What are possible complications of a brachial plexus block?
- Respiratory depression - Horner Syndrome - Hoarseness - Dysphagia
73
Why can respiratory depression occur with brachial plexus blocks?
Hemidiaphragmatic Paresis from Phrenic nerve blockade.
74
What is the triad of Horner Syndrome?
- Ptosis - Miosis - Anhydrosis
75
What are the respiratory consequences of a lateral decubitus position?
(VQ mismatch) - ↓ ventilation of **dependent** lung. - ↑ perfusion of **dependent lung**.
76
During mechanical ventilation in left lateral decubitus patient, which lung is overventilated?
Right lung (nondependent lung)
77
During mechanical ventilation in left lateral decubitus patient, which lung more perfused?
Left lung (dependent lung)
78
Where is an axillary roll placed on a lateral decubitus patient?
Caudad to the axilla to avoid compression of the neurovascular bundle.
79
Where should a pulse oximeter be placed in a lateral decubitus patient?
Dependent hand to ensure that there is no neurovascular compromise
80
Elbow surgeries need what additional block (in comparison to shoulder surgeries) ?
Musculocutaneous nerve
81
Is a patient with a hip fracture induced on the OR table or on the bed/stretcher?
Bed/Stretcher to avoid pain from movement to OR table.
82
What are the benefits of neuraxial anesthesia for hip fracture repairs?
- ↓ delirium - ↓ DVT - ↓ hospital stay - Better pain control
83
What are the three life-threatening complications of total hip arthroplasty?
- BCIS - Hemorrhage - VTE
84
What chemical is bone cement?
PolyMethylMethAcrylate
85
What does bone cement do when introduced to the intramedullary bone surface?
Release heat and pressurize (500mmHg!) Possible embolization of fat, bone marrow, and cement.
86
What is the anesthetic management of BCIS?
- Combat ↓BP and ↓Volume - ↑ FiO₂ & SpO₂
87
What are the s/s of BCIS?
- **Hypoxia** - **Hypotension** - Arrythmias - pHTN - ↓CO
88
In a supine position, spontaneous ventilation favors _______ lung segments, whilst closing volume favors ________ lung segments.
Dependent ; independent
89
The most common postoperative peripheral neuropathy is: a. Ulnar neuropathy b. Brachial plexus injury c. Median nerve injury d. Sciatic nerve compression
a. Ulnar Neuropathy
90
Where are the two major sites of injury in ulnar nerve injury?
Elbow at the **condylar groove** and **cubital tunnel**.
91
How is ulnar nerve nerve injury avoided?
Supinate hands (palms up!)
92
What common drugs are often used for "conscious sedation" of a hip dislocation?
Ketamine/Propofol Mix Succinylcholine
93
What are the possible complications of tourniquet placement for knee surgeries?
- Blood loss on deflation (note for 24hrs) - Peroneal Nerve Palsy
94
What are the steps to a TKA (Total Knee Arthroplasty) ?
1. Tibial Component 2. Femoral Component 3. Patellar Component 4. Plastic Spacer
95
What three conditions (that anesthesia can control) are most often associated with infection of knee replacements?
- Peri-operative glucose control - Post-op hypoxia - Post-op hypothermia
96
What medication classes can be used to treat phantom pain from amputation?
- Neuroleptics - Antidepressants - Na⁺ channel blockers
97
What nerve innervates the plantar surface?
Posterior Tibial nerve
98
What nerve innervates the medial malleolus?
Saphenous nerve
99
What nerve innervates the interspace between the great & 2ⁿᵈ toes?
Deep Peroneal nerve
100
What nerve innervates the space between the dorsum of the foot and the 2ⁿᵈ - 5th toes?
Superficial saphenous nerve
101
What nerve innervates the lateral foot and lateral 5th toe?
Sural nerve
102
A Advanced Principles A (Spring 2024)
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