OSCC

Question 1

Prevalence of OSCC worldwide

Answer 1

1-2%

Question 2

Patients affected

Answer 2

80% are over 40
2M:F
50%+ will die of disease

Question 3

Risk factors for OSCC

Answer 3

Tobacco smokers are 4 times more likely than non smokers
Alcohol drinks are twice as likely. Related to dose
UV or sunlight exposure
Betel quid
Malnutrition
Infections - Candida, syphillis, HPV
Immunosuppression

Question 4

Where are the commonest sites for OSCC?

Answer 4

Tongue
Floor of mouth
Lower gum including retromolar pad
The sump

Question 5

What % of OSCC metastasise?

Answer 5

30-50%

Question 6

What is the three year survival of early and late stage disease?

Answer 6

Early 80%

Late 50%

Question 7

What factors influence prognosis of OSCC?

Answer 7

Site
Age (over 80)
Co morbidity 
Stage especially LN metastasis
Surgical clearance, if margins more than 2mm 33% chance, if margins less than or equal to 2 m 66% of recurrence 
Dysplasia

Question 8

Treatment for OSCC

Answer 8

Surgery
Radiotherapy
Chemotherapy
None of the above