WARFARIN - CI + SE
Pregnancy
active bleeding
risk of major bleeding
SE - bleeding
Diarrhoea, rash, hair loss, nausea
Avoid liver, spinach, cranberry juice, alcohol, nsaids/aspirj
DOAC - CI + SE
Significant renal impairment
major bleeding
active bleeding
SE - bleeding
GI disturbance
Only dab is reversible
Levothyroxine - CI + SE
CI - none
SE - rare, as it is replacing a hormone, could get levels wrong and get symptoms of hyperthyroid
Statin - CI + SE
CI - pregnancy
SE - Muscle pains
Headache
Itching
Nausea, sickness, diarrhea, abdo pain
Rhabdo
Metformin - CI + SE
CI - significant renal impairment
Ketoacidosis
Low BMI
SE - N+D, abdo pain, weight loss
LACTIC ACIDOSIS - let your anaethetist know if taking
Iron tablets - CI + SE
CI - None
SE - GI irritation, black/green stool, funny taste in mouth
SSRI - CI + SE
CI - suicidal risk, mania
SE - GI, appetite and weight change, headahces, anxiety inititally, withdrawal
Sexual dysfunction
Seretonin syndome
Methotrexate - CI + SE
CI - pregnancy INCLUDING MEN
Breast feeding
Hepatic impairment
Active infection
Immunodeficiency
SE - alopecia, headaches, GI disturbance, myelosuppression - seek medical attention of any bruising/bleeding
Liver and lung toxicity
Lithium - CI + SE
CI - 1st trimester of pregnancy
breast feeding
Cardiac insufficiency
renal impairment
addison’s disease
Low sodium diets
SE - GI,
metallic taste
fine tremor
-thirst, polyuria, impaired urinary conc, weight gain, oedema
renal toxicity
nephrogenic DI
hypothyroidism
neuromuscular
Levodopa - CI + SE
CI - glaucoma
SE - psychosis
N+V
Dyskinesias
Postural hypotension
On-off
Impulsive behaviour
dizziness
Insulin - CI + SE
CI - none
SE - weight gain
Sharp injuries
Hypo
Lipidystropy at injection sites
Atypical antipsychotics - CI + SE
CI - hepatic impairment, phaeochroma
SE - anti dopamingerigc
constipation, dry moith
weight gain, dizzines,s drowsiness
NMS - rigidity
agranulo - cloz
Withfrawal
hyperglycaemia + FM
hyperprolactinaemia
prologed QT
