What is osteomyeltitis?
Infection of the bone
What are the routes of infection?
Haematogenous spread
Direct inoculation
Direct spread from nearby infection
What are the common causative organisms?
Staph aureus
Group A strep
Enterobacter
What is a common organism in IVDUs?
Pseudomonas aeruginosa
What is a common organism in sickle cell patients?
Salmonella
What is the pathophysiology of osteomyelitis?
Pathogen settles in bone
Undergoes apoptosis and creates biofilm
Inflammation = subperiosteall reaction -> lifts periosteum from bone
Devitalises bone
What is a sequestrum?
Floating piece of bone
What is an involucrum?
Periosteal new bone
What is a cloaca?
Site of pus escape
Which part of the bone is effected in children?
Metaphysis
- rich blood supply
What are the risk factors for osteomyelitis?
Diabetes
Immunosuppression
Vascular disease
Trauma
What are the clinical features of osteomyelitis?
Severe pain
Systemic symptoms
- fever
Joint effusion
Swelling + erythema
What investigations are required for suspected osteomyelitis?
Bloods
Blood culture
Local culture
X-ray
MRI
How is osteomyelitis managed?
High dose IV abx
Analgesia
Surgery