osteosarcoma

Question 1

age usually presents

Answer 1

adolescents and younger adults aged 10-20

Question 2

most common sites

Answer 2

femur is most common

tibia
humerus

Question 3

presentation

Answer 3

persistent bone pain, worse at night
can disturb sleep

bone swelling
palpable mass
restricted joint movements

Question 4

Mx - children presenting with unexplained bone pain or swelling

Answer 4

very urgent direct access x-ray within 48hrs

Question 5

Mx - xray suggests possible sarcoma

Answer 5

very urgent specialist assessment within 48hrs

Question 6

xray findings

Answer 6

poorly defined lesion

• destruction of normal bone
• fluffy appearance

periosteal reaction with sun-burst appearance

Question 7

blood test results

Answer 7

raised ALP

Question 8

Mx

Answer 8

surgical resection , often with limb amputation

adjuvant chemotherapy

Question 9

main complications

Answer 9

pathological bone fractures

metastasis