osteosarcoma

Question 1

what is it?

Answer 1

malignant bone tumour which produces bone

Question 2

how is metastasis spread?

Answer 2

haematogenous but can be lymphatic

Question 3

who does it commonly affect

Answer 3

adolescents and young adults
elderly patients with Paget’s

Question 4

what does it involve?

Answer 4

bones around knee (distal/proximal tibia)
proximal femur
proximal humerus
pelvis

Question 5

what is management?

Answer 5

surgery

Question 6

why is adjuvant radiotherapy and chemotherapy not used?

Answer 6

are not radiosensitive and not responsive to adjuvant chemo