parathyroid :)

Question 1

what cells secrete PTH ____. this is secreted when??

Answer 1

chief cells
when there is low blood Ca, targeting the bone and kidneys

Question 2

hypoparathyroidism is uncommon, but what are some potential causes? clinicals igns youd see?

Answer 2

• lymphocytic parathyroiditis (immune meidated destruction)
• destruction from metastatic tumor
• parathyroid gland atrophy (like if a tumor elsewehre is making calcium so it goes on vacation)
• accidental surgical removal

C/S: restlness, ataxic, weak, tremors, tetany, seizures

Question 3

primary hyperparathyroidism is the result of…most common in….usually benign or malignant?

Answer 3

functional chief cell neoplasm
common in older dogs
usually adneomas»>carcinomas

Question 4

2 consedquences of excess PTH:

Answer 4

• bone lesions from widespread osteoclastic resorption/fribrous osteodystrophy
• hypercalcemia which interferes with ADH at collectin tubule–>anorexia, PUPD, muscle weakness, soft tissue mineralization

Question 5

secondary hyperparathyroidism is more common than primary. what are the two big causes?

Answer 5

• renal: excess PTH from hypocalcemia and impaired production of Vit D
• nutritional: low calcium, low vit D, or high phosphorus

Question 6

with secondary hyperparathyroidism what will the parathyroid glands look like?

Answer 6

they will ALL be big