Parkinsons

Question 1

where is there widespread degeneration when suffering from Parkinson’s?

Answer 1

substantia nigra - reduction in dopamine

Question 2

Lewy bodies

Answer 2

clumps of proteins in surrounding dopaminergic neuron’s of substantia nigra

Question 3

deep brain stimulation

Answer 3

subthalamic nucleus stimulated

Question 4

anterograde degeneration

Answer 4

distal segment - between the cut and the synaptic terminal

Question 5

retrograde degeneration

Answer 5

proximal segment - between cut and cell body

Question 6

transneuronal degeneration

Answer 6

degeneration spreads to nearby cells

Question 7

remyelination

Answer 7

implantation of stem cells

Question 8

foetal substantia nigra cell implant

Answer 8

successful in monkeys - tardive dyskinesia in humans