passmed misc

Question 1

azathioprine may cause…

Answer 1

myelosuppresion

Question 2

is azathioprine safe in pregnancy

Answer 2

yes

Question 3

ankylosing spondylitis xray findings

Answer 3

subchondral erosins
sclerosis
squaring vertebrae

Question 4

cautions to sulfasalazine

Answer 4

G6PD deficiency

allergy to aspirin or sulphonamides (cross-reactivity)

Question 5

essential test prior to starting biologics for RA

Answer 5

CXR to look for TB

–> they can cause reactivation

Question 6

drug induced SLE - autoantibodies

Answer 6

anti-histone antibodies

Question 7

what should be avoided in eldery patients taking warfarin

Answer 7

NSAIDs

• risk GI haemorrhage

Question 8

patient’s with sjogrens are at increased risk of

Answer 8

lymphoma

Question 9

polyarteria nodosa is assoc with…

Answer 9

hepatitis B

Question 10

antiphospholipid syndrome Mx

Answer 10

primary thromboprophylaxis - low dose aspirin

2ry thromboprophylaxis

• warfarin with INR 2-3
• recurrent VTE - warfarin with INR 3-4

Question 11

diffuse cutaneous sclerosis affects where predominantly

Answer 11

trunk and proximal limbs

Question 12

giant cell arteritis is assoc with what aortic pathology

Answer 12

aortic aneurysm

Question 13

gout x-ray findings

Answer 13

normal joint space
soft tissue swelling
periarticular erosions

Question 14

confirming Dx of antiphospholipid syndrome

Answer 14

1+ of the antibodies present in plasma on 2 occasions 12wks apart

Question 15

monitoring required with leflunomide

Answer 15

BP - baseline and at each review

Question 16

CRP in SLE

Answer 16

usually normal (in contrast to ESR)

Question 17

osteoporosis in man - which blood test

Answer 17

testosterone

Question 18

side effect colchinine

Answer 18

diarrhoea

Question 19

azathioprine + allopurinol

Answer 19

severe interaction causing bone marrow suppression

Question 20

hydroxychloroquine effect on eyes

Answer 20

may result in severe + permanent retinopathy

Question 21

SLE - type of hypersensitivity reaction

Answer 21

type 3

Question 22

blood tests results in osteoporosis

Answer 22

normal

Question 23

most common cause septic arthritis

Answer 23

staph a = overall most common cause

gonorrhoea most common cause in young sexually active adults

Question 24

raised CRP in someone with SLE

Answer 24

underlying infection