Past SAQ notes

Question 1

Causes for Lithium OD in a 32 yo female - presents confused, ataxic, N&V

Answer 1

• pre-renal failure - dehydration
• pregnancy w/ hyperemesis
• UTI
• Li induced nephrogenic DI
• DKA / HHS
• Nephrotoxics (nsaids) -> reduced renal excretion
• Hyponatraemia
• Acute OD in setting of chronic ingestion

Question 2

Antibiotics for UTI in pregnancy - considerations

Answer 2

Safe antibiotics:
- Nitrofurantoin (avoid after 36/40)
- Amoxycillin: safe in pregnancy but may be resistant
- TMP: folic acid antagonist –> risk of NTD, after T1
- Cephalexin safe in pregnancy

Less optimal antibiotics:
- Tetracyclines - avoid –> fetal tooth discoloration
- Norfloxacin - renal abnormalities
- Ciprofloxacin - fetal cartilage / bone defects

Question 3

Drugs that can be eliminated by HD

Answer 3

Li, K
Toxic alcohols
Carbamazepine, Na valproate, phenobarbitone
Salicylate, Theophylline

Question 4

Drugs that will not bind to AC

Answer 4

toxic alcohols - methanol, ethylene glycol, isopropyl glycol, ethanol
heavy metals - iron, lead, potassium, mercury, arsenic, cyanide
acids/alkali