PATH - General

Question 1

Neutropenia

Answer 1

-Absolute neutrophil count

Question 2

Lymphopenia

Answer 2

Absolute lymphocyte count

Question 3

Eosinopenia

Answer 3

Absolute eosinophil count

Question 4

Langerhans cell histiocytosis

Answer 4

Collective group of proliferative disorders of
dendritic (Langerhans) cells

express *S-100 and
*CD1a.

**Birbeck granules (“tennis rackets” or rod shaped on EM)

Presents in a *child as lytic bone lesions and skin rash or as recurrent otitis media with a mass involving
the mastoid bone

Cells are functionally immature and do not effectively stimulate
primary T cells via antigen presentation