Patho 2- Multiple Sclerosis

Question 1

Definition of multiple sclerosis

Answer 1

Chronic, demyelinating disease of CNS
Inflammatory process causing CNS degeneration
Severe neurological deficit

Question 2

Suspected triggers of MS

Answer 2

Infection
Vaccination 
Pregnancy 
Trauma
Emotional stress
Environmental factors
Viral factors
Genetics
Diet deficits

Question 3

Pathology of MS

Answer 3

Disruption of blood brain barrier
Leakage of inflammatory cells
Disruption of oligodendrocytes and myelin sheath
Disruption of nerve signals, rate of conduction slowed down
Plaques form throughout CNS

Question 4

Types of MS

Answer 4

Silent/Benign
Relapsing-Remitting
Secondary progressive
Primary progressive

Question 5

Signs and symptoms of MS

Answer 5

Visual problems
Weakness
Spasticity and hyperflexia decreased
Ataxia and poor coordination 
Sensory loss
Dizziness and poor balance
Sphincter disturbance and sexual dysfunction 
Psychiatric and psychological disturbance 
Decreased intellectual function 
Fatigue