Pathology

Question 1

Myocardial infarction is an example of what type of necrosis

Coa

Answer 1

Coagulative necrosis

Question 2

Example of caseating granuloma

TB

Answer 2

Tuberculosis

Question 3

Virchov’s triad

Answer 3

Endothelial damage
Stasis/turbulence of blood flow
Hypercoagulability

Question 4

Factor V leiden mutation predisposes to

c

Answer 4

Increased thrombosis risk

Question 5

Most common site of endometriosis deposits

Answer 5

Ovaries

Question 6

Complete molar pregnancy - karyotype and DNA origin?

Answer 6

46XY/46XX
Paternal DNA only

Question 7

Partial molar pregnancy - karyotype and DNA origin

Tr

Answer 7

Triploid
Maternal and Paternal DNA

Question 8

Complete molar pregnancy - risk of choriocarcinoma

Answer 8

2%

Question 9

Placental site trophoblastic tumour - tumour marker

H

Answer 9

Human Placental Lactogen

Question 10

Aflatoxin B1 is associated with which neoplasm

Answer 10

Hepatocellular carcinoma

Question 10

Aniline dyes associated with which neoplasm

Answer 10

Bladder

Question 11

Yolk sac tumour - tumour marker

Answer 11

AFP

Question 12

Gardasil 9 - HPV subtypes

Answer 12

6, 11, 16, 18, 31, 33, 45, 52 and 58.

Question 13

What are the three types of endometrial cancer

Answer 13

1. Endometroid adenocarcinoma (type 1) - unopposed oestrogen, younger, better prognosis
2. Serous adenocarcinoma (type 2) - poorer prognosis, older women, no associated with unopposed oestrogen
3. Clear cell carcinoma (type 2)

Question 14

Examples of type 1 ovarian tumours

Answer 14

Mucinous carcinoma
Endometroid carcinoma

Develop from well-established precursor lesions ‘borderline tumours’