IL involved in coagualtion
secreted by macrophages ad muscle
IL6
what cells are phagocytic
neutrophils
macrophages
monocytes
kuppfer
Mx of hereditary angioedema
fresh frozen plasma
what mediator is formed by mast cell
thromboxane
MoA of ciclosporin
inhibiting release of IL2 from T cells
Role of kinins
attract phagocytes
Mcrophages
from monocytes and phagocytosis
which immunoglobin responsible for anaphylaxis
IgE
endothelin 1
Vasoconstrictor -> polypeptide
complemetn role
kills everything
activated by alternate natural coag casacde
which cytokine secreted by macrophages and muscles
IL6 - involved in coagulation cascade
Mx of hereditary angioedema
deficiency if C1 esterase inhibitor
FFP
gene ass with li framrni syndrome
p53
Granulation tissue consists of
fibroblasts proloferation of new capillaires
Hep B and C composition
Hep b DS DnA
Hep C single stranded rna
Role of chlorhexidine
Bacterial cell membrane disruption
most commonest site for osteomyelitis in IVDU
Femoral metaphysis
celly type of barretts
goes from stratified to simple columnar epithelium
BrCA1 which chromosome
17
Lymphocytic lobulitis
T1dm mimics cancer
How does sickle cell show on blood fil
normochromic normocytic anaemia
high reticulocyte count
what is anasarca
condition characterised by widespread swelling of the skin due to effusion of fluid into the extracellular space. It is usually caused by either cardiac failure, liver failure or renal failure. It can also be created from the administration of exogenous intravenous fluid. Certain plant-derived anticancer chemotherapeutic agents, such as docetaxel, cause anasarca through a poorly understood capillary leak syndrome.
ECG changes of hypokalaemia
sagging of the ST segment, depression of the T-wave and elevation of the U-wave
