pathology adaptations

Question 1

atrophy

Answer 1

decrease in size and or volume of cells and tissue in an organ

Question 2

hypertrophy

Answer 2

increase in cell size resulting in increase in volume of an organ

Question 3

hyperplasia

Answer 3

increase in cell numbers resulting in an increase in volume of an organ

Question 4

metaplasia

Answer 4

replacement of one adult cell type by another adult cell type

Question 5

dysplasia

Answer 5

• disordered growth - failure of normal differentiation

- always pathologic

Question 6

where does normal hyperplasia occur?

Answer 6

can occur in prostate, breast

Question 7

where does normal metaplasia occur?

Answer 7

cervix - physiologic squamous metaplasia

Question 8

barrett esophagus

Answer 8

• metaplasia and dysplasia
• pathophysiologic response to chronic gastrointestinal reflux
• starts as hyperplasia and leads to metaplasia
• untreated may lead to dysplasia (cancer)

Question 9

bronchial metaplasia

Answer 9

squamous epithelium