pathophysiology

Question 1

asthma

Answer 1

type 1 hypersensitivity reaction where mast cells release histamine and inflammatory mediators leading to chronic inflammation, airway oedema, mucous production and bronchoconstriction

Question 2

why lower oxygen targets in copd

Answer 2

used to a chronic state of hypercapnia meaning that the respiratory drive is based only off of hyperaemia. If give too much oxygen they lose their hypoxic drive so reparation is compromised

Question 3

why does appendix pain start periumbilical then migrate to rif

Answer 3

Visceral peritoneum has no somatic innervation so felt at the dermatome - T10
As disease progresses, parietal peritoneum becomes affected which has somatic innervation so able to be localised