PBL: MI Flashcards by Robbie Gruhl

Q

Heparin

MOA

A

catalyst for binding

antithrombin III + thrombin/Factor X_a

=> neutralization

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Q

Aspirin

MOA

A

irreversibly binds COX-1 on platelets

prevents platelet aggregation

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Q

Clopidogrel

MOA

A

ADP receptor antagonist

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Q

Nitroglycerin

MOA

A

G-protein second messenger

vasodilation, esp. on venous side

decrease preload

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Q

Morphine MOA

A

mu receptors

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Q

Mode of inheritance

Familial Hypercholesterolemia

A

autosomal codominant

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Q

Familial hypercholesterolemia

possible mutations

A

low-density lipoprotein receptor (LDLR)

apolipoprotein B (APOB)

pro-protein convertase subtilisin-kexin 9

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Q

A

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