PDD 01: Module Introduction

Question 1

What are the best dosage forms for systemic use?

Answer 1

• oral – tablet/capsule
• rectal – tablet/capsule
• IV
• IM
• transdermal patch

Question 2

What are the best dosage forms for local use?

Answer 2

• transdermal patch
• topical cream/lotion
• eye drops
• ear drops

Question 3

What are some therapeutic considerations for dosage forms for emergency use?

Answer 3

• rapid onset
• unconscious patient

Question 4

What are the best dosage forms for emergency use?

Answer 4

• IV
• IM
• sublingual
• inhalation

Question 5

What are some therapeutic considerations for dosage forms for young children?

Answer 5

• liquid
• taste
• user-friendly device

Question 6

What are some therapeutic considerations for dosage forms for elderly?

Answer 6

• liquid
• user-friendly device
• uncomplicated dosing
• sustained-release dosage form

Question 7

What are excipients?

Answer 7

pharmaceutical ingredients in a dosage form other than the active agent

• have significant effects on efficacy of drug

Question 8

What are some excipients that increase solubility? (2)

Answer 8

• solvents
• surfactants

Question 9

What are some excipients that increase palatability? (1)

Answer 9

sweeteners

Question 10

What are some excipients that increase stability? (2)

Answer 10

• antimicrobials
• antioxidants

Question 11

What are some ‘other’ (ie. tablet) excipients? (4)

Answer 11

• diluents (fillers)
• binders
• lubricants
• disintegrating agents

Question 12

What is the importance of diluents?

Answer 12

safe and convenient delivery of accurate dosage

Question 13

What is the importance of solubilizers?

Answer 13

IV formulation