1
Q
What is peptic ulceration?
A
A breach in the GI mucosa as a result of acid and pepsin attack. It is a special type of gastric inflammatory disease
2
Q
What are the common sites of chronic peptic ulcers?
A
1st part of duodenum
Stomach
Oesophago-gastric junction
Stomal ulcers
3
Q
What is stomal ulceration?
A
This is when there is failure pf a previous gastric operation to control peptic ulcer disease
4
Q
What is the microscopic appearance of peptic ulcers?
A
Layered appearance
Floor of necrotic fibrinopurulent debris
Base of inflamed granulation tissue
Deepest layer is fibrotic scar tissue
5
Q
What are the complications of peptic ulcers?
A
Perforation Penetration Haemorrhage Stenosis Intractable
