Peptides

Question 1

Carnitine structure

Answer 1

Tri-methyl lysine

Question 2

Carnitine function

Answer 2

Transport of FAs into mitochondria

Question 3

What does carnitine require?

Answer 3

• SAMe
• Vitamin C
• Fe
• NAD+
• B6

Question 4

Where is carnitine made?

Answer 4

• Liver
• Kidney

Question 5

Where is carnitine stored?

Answer 5

Muscle

Question 6

Creatine structure

Answer 6

Arginine + Glycine

Question 7

Creatine function

Answer 7

Source of energy as creatine phosphate
Enzyme: Creatine kinase

Question 8

Where is creatine made?

Answer 8

• Liver
• Kidney

Question 9

Where is creatine stored?

Answer 9

Muscle (require SAMe)

Question 10

Glutathione structure

Answer 10

Glu-Cys-Gly

Question 11

Glutathione function

Answer 11

Antioxidant in RBCs and liver

Question 12

What does glutathione require?

Answer 12

• Glutathione peroxidase (Se)
• Glutathione reductase (NADPH and FADH2)

Question 13

Endorphins structure

Answer 13

Peptide

Question 14

Endorphin function

Answer 14

• Receptors in brain, gut and WBCs
• Runners high, joy

Question 15

Bradykin structure

Answer 15

Peptide

Question 16

Bradykin function

Answer 16

Smooth muscle hypotensive agent released in response to tissue damage

Question 17

What does bradykin begin?

Answer 17

Arachidonic cascade (pain and inflammation pathway)

Question 18

Insulin structure

Answer 18

Peptide with disulfide bond

Question 19

Insulin function

Answer 19

What: Binds to the Glut 4 receptor
Where: in muscle and adipose tissue
Why: to allow glucose to enter the cell

Question 20

What is insulin not needed for?

Answer 20

• Glut 1: RBC and brain
• Glut 2: Liver

Question 21

What peptides require SAMe?

Answer 21

• Carnitine
• Creatine