Peripheral neuropathy

Question 1

What is peripheral neuropathy?

Answer 1

Nerve pathology outside CNS, of peripheral nerves

Question 2

What are the mechanisms of peripheral neuropathy?

Answer 2

Demyelination
axonal damage
nerve compression
vasa nervorsum infarction
Wallerion degeneration (nerve cut - distally dies)

Question 3

Causes of peripheral neuropathy?

Answer 3

Demyelination (Guillain barre, B12 def)
T2DM
Surgery
Pathology eg. infection, endocrine, RA…

Question 4

What is mononeuropathy?

Answer 4

Single nerve

Question 5

What is mononeuritis multiplex?

Answer 5

Several individual nerves

Question 6

What is polyneuropathy?

Answer 6

Diffuse, often symmetrical pathology

Question 7

Mononeuritis multiplex causes?
acronym

Answer 7

WARDS PLC

Wegeners
AIDS/amyloidosis
RA
DMT2
Sarcoidosis
Polyarteritis nodosa
Leprosy
Carcinomas