Pharm I

Question 1

ED 50

Answer 1

Effective dose
- Dose that produces the expected clinical response (therapeutic effect) in 50% population
Measures potency

Question 2

TD 50

Answer 2

Toxic dose
- Dose that produces a toxic effect in 50% population

Question 3

LD 50

Answer 3

Lethal dose in 50% population

Question 4

Therapeutic Index

Answer 4

LD 50 / ED 50
Measures drug safety

Question 5

Therapeutic Window

Answer 5

TD 50 / ED 50

Question 6

Total Body Water

Answer 6

42 L