1
Q
Why shouldn’t a patient take both a ACEi and an ARB to treat their hypertension?
A
No two drugs that act seperately on the RAAS shou’d be used in combination?
2
Q
Name three mechanisms by which angiotensin 2 increases BP?
A
- Increases sympathetic activity
- vasoconstriction
- stimulates aldosterone release
3
Q
What is a common reason that patients switch to an ARB in place of an ACEi?
A
They develop a dry cough as a side effect of the ACEi meds.
4
Q
Which antihypertensive is not suitable if there is a history of heart failure and why?
A
CCBs. They reduce strength of contraction which counters the bodys natural compensation to HF.
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