Pharmacology

Question 1

What is the mechanism of baclofen?

Answer 1

acts on GABA B receptors in the spinal cord to decrease release of excitatory neurotransmitters

Question 2

What is a starting dose of baclofen in the pediatric population?

Answer 2

2.5mg BID

Question 3

What is the drug of choice of spasticity of cerebral origin?

Answer 3

dantrolene

Question 4

mechanism of action of clonidine and tizanidine?

Answer 4

alpha 2 agonist