Phase 2 - Resp

Question 1

Common microbial colonisers of airways in Cystic Fibrosis

Answer 1

• S Aureus
• H Influenzae
• Klebsiella pneumoniae
• E coli
• Burkhodheria cepacia
• PSEUDOMONAS AERUGINOSA (particularlly hard to treat - can become resistant to multiple antibiotics) - the reason it is now discouraged to have group meet ups for children with cystic fibrosis

Question 2

Treatment of pseudomonas colonisation in airways

Answer 2

• Nebulised Tobramycin
• Oral ciprofluxacin

Question 3

Causes of Type 2 resp failure

Answer 3

• Airways obstruction (COPD, v severe Asthma)
• Alveolar hypoventilation
  
  • Emphysema
  • Obesity (e.g. in sleep apnea)
  • Reduced resp drive (e.g. on opiates)
  • Muscular weakness (MND)