Antimicrobials > Phenicolé > Flashcards

Phenicolé Flashcards

(6 cards)

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1
Q

Membres de la classe

A

Chloramphenicole

Thiamphenicole

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2
Q

MoA

A

Inhibiteurs de la synthese proteique en se fixant sur le site A an niveau de la ss 50S

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3
Q

Effet

A

Bacteriostatique

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4
Q

Indications therapeutique

A

Fievre typhoïde
Meningite
Infections broncho-pulmonaire
Infection hepato-biliaire
Infection grave par Bacteroides fragilis
Rikettsiose non sensible a la tetracycline

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5
Q

Effets indesirables

A

Hypoplasie medullaire
Aplasie medullaire
Anemies hemolytiques chez patients deficient en G6PD
Symptomes neuropsychique

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6
Q

Contre indications

A

Enfant agée de moins de 3mois

Femme enceinte a terme ou nourisson

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