Why is Pk important
It represents the pH at maximum buffering capacity
What is Pk?
The pH value at which the solute is 50% dissociated
What is the Pk of bicarbonate and carbonic acid?
6.1
What is the solubility coefficient of CO2?
.03
What is the pressure of CO2 in torr?
40 torr
What formula is used to find a the ph of 7.4?
Ph= 6.1 + log (24mEq-L)/(40)(.03)
Ficks law of diffusion
A = cross sectional area
D = diffusion coefficient
T = thickness of membrane
P1 - P2 = pressure gradient
Alveolar epithelium
Interstitial space
Capillary endothelium
3 barriers to diffusion
Ficks law of diffusion formula
Vgas= A • D(p1-p2)/T