Plague

Question 1

Plague is mainly a disease of ____

Answer 1

rodents

Question 2

most severe Plague in history

Answer 2

Black Death
(75-200M deaths)

Question 3

3 biovars of Plague

[ amo ]

Answer 3

Antiqua
Medievalis
Orientalis

Question 4

2 biovars in Central Asia

Answer 4

Antiqua & Medievalis

Question 5

biovar in Africa

Answer 5

Antiqua

Question 6

biovar that is widespread

Answer 6

Orientalis

Question 7

most affected place due to Plague

Answer 7

Madagascar (endemic)

Question 8

(2) preferred season of Plague

Answer 8

1. summer
2. spring

warm temp
high relative humidity

Question 9

Occurence of Plague

Answer 9

• remote places
• delay in dx & tx

Question 10

Natural disaster & destruction of habitat caused widespread of ___, increasing Plague transmission.

Answer 10

fleas

Question 11

Incidental host for plague

Answer 11

Humans

Question 12

Plague

vector —
IH —

Answer 12

vector — fleas
IH — rodents

Question 13

optimal growth temp of Plague

Answer 13

30 C (capable at 4C — 41C)

Question 14

What fomites can Plague survive in? (2)

Answer 14

soil
steel

Question 15

ID of Plague?

clue - low

Answer 15

1 - 10

Question 16

(4) diseases of Plagues in HUMANS

Answer 16

1. Bubonic
2. Septicemic
3. Pneumonic
4. Rare

Question 17

(2) diseases caused by flea bite

Answer 17

1. Bubonic
2. Septicemic

Question 18

more common septicemic form

Answer 18

2 Septicemic (secondary)

Question 19

(1) primary septicemic form

[ ehp ]

Answer 19

1. epistaxis
2. hematuria
3. petechiae

Question 20

the zoonotic Plague

Answer 20

Septicemic form

Question 21

Human-Human transmission Plague caused by:

primary — INHALATION
secondary — infected blood to LUNGS

Answer 21

Pneumonic form

Question 22

most common Plague

Answer 22

Bubonic

Question 23

self-limiting plague

Answer 23

Rare form (pestis minor)

Question 24

Plague that causes swollen femoral lymph nodes as clinical signs

Answer 24

Bubonic form

Question 25

Plague bacteria per: • blood meal — • bite —

Answer 25

• blood meal — 300 • bite — 20,000

Question 26

Plague case fatality of bubonic form w/o treatment

Answer 26

50-70%

Question 27

Plague case fatality of Bubonic form with treatment

Answer 27

10-15%

Question 28

Plague case fatality of Septicemic form with treatment

Answer 28

40%

Question 29

(2) with 100% case fatality rate w/o treatment

Answer 29

1. Septicemic 2. Pneumonic

Question 30

100% case fatality rate with or w/o tx

Answer 30

Pneumonic form

Question 31

(3) Case definitions of Plague [ San Pablo City ]

Answer 31

1. Suspected 2. Presumptive 3. Confirmed

Question 32

Case definition involved in • clinical signs • epidemiological feature • flea bite evidence • travel to endemic places in previous 10 days

Answer 32

Suspected case

Question 33

consistent with 2 out 4 positive tests • gram negative coccobacilli • Wayson / Giemsa • F1 antigen (ELISA / dipstick) • single anti-F1 serology

Answer 33

Presumptive case

Question 34

In serologic tests, any previous exposure of Plague leads to?

Answer 34

false-POSITIVE

Question 35

case with 2 out of 4 positive BACTERIAL CULTURE

Answer 35

Confirmed case

Question 36

(2) virus used in lysis of bacteria ng Plague • 20-25C • 37C

Answer 36

1. Podo-viridae 2. Myo-viridae

Question 37

Biochemical profile of Plague IMViC

Answer 37

IMViC ( - | + | - | - ) catalase = (+)

Question 38

most common form of Plague in CATS

Answer 38

bubonic form

Question 39

resistant to Plague

Answer 39

rodents

Question 40

Type of plague for GOATS & CAMEL

Answer 40

OCULAR plague

Question 41

type of hemorr septicemia in rodents with Plague

Answer 41

Subclinical / Fulminant

Question 42

Not known to develop Plague x CHiPS x

Answer 42

Cattle Horse Pig Sheep

Question 43

stains for Plague (2)

Answer 43

1. Wright-Giemsa 2. Wayson

Question 44

samples for nutrient agar of Plague (3)

Answer 44

1. blood 2. bubo aspirates 3. sputum

Question 45

interval of latex agglutination for Plague

Answer 45

1 - 2 weeks interval

Question 46

most important prevention for Plague

Answer 46

early diagnosis

Question 47

1st line of antibiotics for Plague

Answer 47

Cotrimoxazole

Question 48

other antibiotics for Plague [ sdc ]

Answer 48

Streptomycin Doxycycline Chlorampenicol

Question 49

route of vaccine for high risk group of Plague give interval

Answer 49

IM (weeks 1, 5, 6)