Blood responsible for the source of phospolipid
Platelets
What is responsible for the production of platelets in the bone marrow?
Megakaryocytes, under the influence of thrombopoeitin.
How is platelet produced?
A megakaryocyte is first invaginated and a cytoplasmic island is formed. When the cytoplasmic islands are fragmented, a platelet is formed.
T or F
Platelets are granulated.
T
ADP or ATP
What is responsible in aiding the platelets’ change of shape in response to their adherence to a damaged tissue?
ADP
Define von Willebrand factor
The adherence of circulating platelets to a damaged tissue. Particularly the endothelium
Define hemostatic plug
Local accumulation of fibrin and platelets
Platelet count before the risk of hemorrhagic distress.
<30 000/microliter
Decrease in three hematologic cell line
Pancytopenia
T or F
Most thrombocytosis and thrombocytopenia are rare and often idiopathic.
F - thrombocytosis is rare, but thrombocytopenia is undocumented to be idiopathic.
T or F
Myeloproliferative diseases can cause sequestration of platelets.
T
Name one drug which causes platelet aggregation.
Aspirin
(charot, corticosteroid dapat, prednisone, prednisolone, and dexamethasone. Aspirin causes platelet decumulation)
What happens when thromboxane’s mechanism of action is inhibited by a drug?
Hemostatic plug and platelet aggregation is compromised.
