Platlet Properties
Adhesion
Aggregation
Activation n release
Adhesion
Facilit vWF
Stick to exposed collagen, non/subendothelial surfaces-vWF….via GpIb on surface of plt
Blood disorder, memb protein deficiency
GpIb receptor abs-bernard soulier syndrome
vWF in plasma-vW disease
Defective platelet adhesion
Aggregtion
Stick to each other
Facilit- fibrinogen, GpIIb, GpIIIa
And thrombin, adp, paf
Secretion
Activation- thrombin, adp
Oval to spherical,pseudopodia-contraction of actinomycin…on activ
Plat rel, open canalic syst, granular cont, seretonin