Functions of PPP
Produces NADPH
Produces ribose-5-phosphate
Metabolic use of 5-carbon sugars
What pathway is responsible for synthesis of nitric oxide
HMP shunt
How many ATPs are used by the PPP?
None. No consumption or production of ATP
Rate limiting enzyme in PPP
Glucose 6-P dehydrogenase (G6PD)
Two phases of PPP
Oxidative phase (irreversible) Non-oxidative phase (reversible)
Products of oxidative phase of PPP
NADPH (2)
Ribulose-5-P
Enzyme in non-oxidative phase of PPP
Transketolase
Co-factor for transketolases
Vitamin B1
Enzyme and co-factor for used by reduced glutathione sequestering of harmful H2O2
Glutathione peroxidase
Co-factor: selenium