Oxidative vs Non-oxidative pathway
Oxidative produces NADPH, non-oxidative produces glycolytic intermediates without producing ribose
G6PDH Deficiency
decreased NADPH, leads to decreased reduced glutathione (GSH), decreased lipid oxidation, decreased RBC membrane integrity
Symptoms: neonatal jaundice, acute hemolytic anemia triggered by certain drugs
Xylulose-5P combines with Ribose-5P to create what
Glyceraldehyde-3P and Sedoheptulose-7P
Glceraldehyde-3P and Sedoheptulose-7P combine to create
Fructose 6P and Erythrose 4P
Erythrose 4P combines with Xylulose-5P to create
F6P and glyceraldehdye-3P