Which drug is a calcium channel blocker used to treat hypertension?
Amlodipine
What does ED50 represent?
Effective dose in 50% of subjects
Which route of administration has the highest bioavailability?
IV
What is ED50?
Effective dose of drug in 50% of subjects
How would you describe a pro-drug?
A biologically inactive compound which can be metabolised in the body to produce a drug
Which antibiotic would you prescribe for a gram-negative organism?
Gentamicin
Which symptom is most associated with hypothyroidism?
Weight gain
What type of interaction describes reduced absorption of bisphosphonates by food or cations?
Pharmacokinetic
Why is it important to monitor gentamicin levels?
It has a narrow therapeutic range
What test should be used to check kidney function in a patient taking ramipril?
eGFR
Which antidepressant is least appropriate for a frail elderly patient due to risk of falls?
Amitriptyline
What should you advise a patient who develops nausea after starting citalopram?
Advise that it’s a common side effect and usually resolves within days, so keep taking.
What antibiotic is least associated with risk of C. diff infection?
Flucloxacillin
What does Gram-positive mean?
The purple dye is taken up by the cell wall
Which bacteria look like rods under a microscope?
Bacilli
Which medication is NOT used in the primary treatment of hyperthyroidism?
Levothyroxine
Which medication is used for the treatment of hypothyroidism?
Levothyroxine
Which antibiotic would you use for a gram-positive infection?
Flucloxacillin
Which medication is an isomer of another well-known SSRI?
Escitalopram
Which antidepressant is most toxic in overdose?
Imipramine
Which action would NOT help prevent antimicrobial resistance?
Continuing parenteral antibiotics for the full course (5–7 days)
The regular use of which medicine is most likely to cause secondary hypertension?
Oestrogen-containing oral contraceptives
Which medicine reduces blood pressure by blocking Ca²⁺ entry into vascular smooth muscle cells?
Amlodipine
Which of the following best describes an agonist?
A drug that activates receptors
