Intoxicaciones > Pralidoxima > Flashcards

Pralidoxima Flashcards

(7 cards)

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1
Q

Indicaciones

A

Coadyuvante en intoxicación por organofosforados malatión y paratión

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2
Q

Mecanismo de acción

A

Reactiva a la enzima colinesterasa por la interacción de su grupo oxima al lugar esterástico fosforilado por el organofosforado

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3
Q

Administración

A

Vía intravenosa

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4
Q

Distribución

A

Amplia, no atraviesa barrera hematoencefálica

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5
Q

Vida media

A

75 minutos

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6
Q

RAM

A

Crisis convulsivas
Apnea
Espasmo laríngeo
Paro cardiaco

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7
Q

Contraindicaciones

A

Pacientes en tratamiento con inhibidores de la colinesterasa

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