Triple Assessment
Clinical assessment
Imaging assessment - mammography / ultrasound / both
Needle biopsy
Scoring
1 - Normal 2 - Benign 3 - Intermediate / equivocal 4 - Suspicious 5 - Malignant
Predisposing factors to breast cancer
BRCA genes 1st degree premenopausal relative with breast cancer Nulliparity, first child > 30 Early menarche, late menopause HRT / combined OCP Past breast cancer Not breast feeding Ionising radiation p53 gene mutations Obesity Past surgery for benign disease
Mammography
X-ray of breast
MLO and CC views
Compression - spread out the tissue, holds breast still, reduces radiation dose needed
Much less effective in dense tissue (higher proportion of fibroglandular tissue compared to fat)
Ultrasound
Uses high-frequency sound waves to form an image of tissues.
Technique of choice in women < 40
Good at distinguishing cystic from solid masses - fluid appears black, solid appears varying shades of grey
Shape and margin!