➢ Show organs or parts of the body
in contrast to their surrounding
tissue.
➢ Increase differential attenuation
between a soft tissue structure and
surrounding tissue
contrast media/agent
negative
– used to increase organ density & improve radiographic visualization
➢ High atomic number
positive
positive and negative contrast
agent
double contrast
➢ A suspension which is dry powder
or premixed.
➢ Properties:
1. high atomic number
2. insoluble and stable
3. little upset to the intestinal
tract even in large doses
4. cheap
BaSO4
Iodinated Contrast Agent
not readily absorbed by the
body
oil based
high osmolality
ionic
low osmolality
non-ionic
measure of the total number of
particles in solution/kg of H2O
osmolality
fluidity
Viscosity
may have adverse effects on cardiovascular system.
calcium binding
stable for 5 years
chemical stability
Categories of LOCM:
MODE OF ADMINISTRATION
Sensitivity Testing:
Clinical Manifestation of Expected Side Effects
Clinical Manifestation of a Vasovagal Reaction
Clinical Manifestations of a Moderate Adverse Reaction
Clinical Manifestation of a Moderate Adverse Reaction
Clinical Manifestations of a Severe Anaphylactic Reaction
result of an exaggerated hypersensitivity reaction to re-exposure to an antigen
that was previously encountered by the body’s immune system.
Anaphylactic Shock
Classification of Clinical Manifestations:
mild systemic reaction