Prelim | Dose Forms

Question 1

Manner on how drugs are being prepared/ how chemical agents are being transported in the bofy

Answer 1

Dose forms

Question 2

DOSE FORM CLASSIFICATION

Answer 2

1. ROUTE OF ADMINISTRATION
2. PHYSICAL FORM

Question 3

ROUTE OF ADMINISTRATION

Answer 3

1. Oral
2. Parenteral
3. Transdermal
4. Respiratory/ Inhaled
5. Ophthalmic
6. Rectal
7. Vaginal
8. Otic

ROOT PROV

Question 4

PHYSICAL FORM

Answer 4

1. Solid
2. Semi-solid
3. Liquid
4. Gases

Question 5

Most common oral dose and one of the easiest to administer (for adults)

Answer 5

Tablet

Question 6

A granulated drug that has been compressed into a solid hard disk.

Answer 6

Tablet

Question 7

Single-dose units that may be scored to facilitate division into halves or quarters.

Answer 7

Tablet

Question 8

Buccal, Sublingual, Dispersible, chewable, film-coated, enteric-coated, effervescent, etc.

Answer 8

Tablet

Question 9

Coated on animal skin/ product

Answer 9

Enteric-coated

Question 10

A dose form in which a powdered or liquid drug is contained in a gelatin shell.

Answer 10

Capsule

Question 11

The gelatin shell (proteins extracted from animal collagen) dissolves in the
stomach and releases its contents.

Answer 11

Capsule

Question 12

Gelatin shell of capsules are extracted from —

Answer 12

animal collagen

Question 13

Types of capsule

Answer 13

Hard capsule
Soft gelation capsule

Question 14

Hard capsule vs Soft gelation capsule

Answer 14

Hard capsule: low moisture content; powder, pellet, granules

Soft gelation capsule: high moisture content; ex. fish oil, keratin

Question 15

A solid preparation that used to medicate the mouth and throat for the slow administration of indigestion or cough remedies.
* can also be for chest decongestion

Answer 15

Lozenges

Question 16

Lozenges consists of (1) and (2), the latter giving strength and cohesiveness to the lozenge and facilitating (3) of the medicament.

Answer 16

1. sugar
2. gum
3. slow release

Question 17

A solid medicated pill or candy preparation that design to dissolve slowly in the mouth.

Answer 17

Pastilles

Question 18

Pastilles are softer than lozenge and their base are —

Answer 18

Glycerol, gelatin, acacia and sugar

Question 19

Pastilles main absorption sire

Answer 19

Tongue, buccal, intestines

Question 20

A small rounded dosage form containing medicaments mixed with additives.

Answer 20

Pills

Question 21

Commonly found on OCs (oral contraceptives)

Answer 21

Pills

Question 22

Pills vs tablets

Answer 22

Pills: mixed with additives
Tanlet: Pure content of medication

Question 23

Consists of solid, dry aggregates of powder particles with irregular shape often supplied in single-dose sachets.

Answer 23

Granules

Question 24

Some — are placed under the tongue and swallowed with water and other are intended to be dissolved in water before taking.

Answer 24

granules

Question 25

It is a dose form shaped for insertion into a body orifice such as the rectum.

Answer 25

Suppository

Question 26

Once inserted, the suppository dissolves and (1). It may have (2) or (3) effect.

Answer 26

1. releases the drug 2. local 3. systemic

Question 27

Semi-solid medicated preparation designed for insertion into the vagina where they melt

Answer 27

Pessaries

Question 28

Common content of pessaries

Answer 28

1. antiseptics 3. Contraceptive agents 3. Local anesthetic

Question 29

Semi-solid, medicated preparations for application to the skin, rectum, or nasal mucosa.

Answer 29

Ointment

Question 30

Ointment base is usually (1) and (2) with skin secretions.

Answer 30

1. anhydrous 2. immiscible

Question 31

A --- is constrained with 3D poymetric matrix (consists of natural or synthetic gum), having a high degree of physical or chemical cross-linking.

Answer 31

gel liquid phase

Question 32

A semisolid dosage form containing one or more drug substances dissolved or dispersed in a suitable base (oil/ water)

Answer 32

Creams

Question 33

Dose form in which one or more drugs are dissolved in a liquid carrier.

Answer 33

Solution

Question 34

Usually rapidly absorbed and may be administered orally or parentally.

Answer 34

Solution

Question 35

Stabilized oil-in-water dispersions, either or both phases of which may contain dissolved solids either oil is dispersed in finely divided form in water or vice versa.

Answer 35

Emulsion

Question 36

Liquid-in-liquid despersion (immiscible)

Answer 36

Emulsion

Question 37

Solution vs Emulsion

Answer 37

Solution: Pure chemical content placed in a bottle; DON'T shake Emulsion: Does not mix with other chemical content of product; NEEDS to be shaken

Question 38

It is a dose form in which one or more drugs in small particle are suspended in a liquid carrier.

Answer 38

Suspension

Question 39

Most suspensions are administered (1) and should be (2) thoroughly just before administration.

Answer 39

1. orally 2. shaken

Question 40

Suspension should never be administered ---

Answer 40

intravenously

Question 41

It is a concentrated aqueous solution of a sugar, usually sucrose to which medicaments are added.

Answer 41

Syrup

Question 42

solution of nitro cellulose in ether or acetone, some times with the addition of alcohols.

Answer 42

Collodion

Question 43

Collodion is composed of (1) for treatment of scar, warts, and other skin conditions.

Answer 43

1. pyroxillin

Question 44

Intended to be administered in small volumes with the aid of a suitable measuring device. Oral, Eye, Ear, or Nasal administration

Answer 44

Drops

Question 45

The --- route of administration may be used for either local or systemic effects (general anesthetics).

Answer 45

inhalation

Question 46

Allow high concentrations to be deposited in the respiratory mucosa and exert action by producing bronchodilation or reducing inflammation.

Answer 46

Inhaler

Question 47

Release of a dose of the medicament under pressure in an aerosol dispenser in the form of droplets of 50 um diameter or less from the container through a spring loaded valve incorporating a metering device.

Answer 47

Inhaler

Question 48

It is commonly used in the treatment of asthma and other respiratory problems.

Answer 48

Inhaler

Question 49

It is commonly used in treating asthma, and other respiratory diseases.

Answer 49

Nebulizer/ Atomizer

Question 50

It is a device used to administer medication in forms of a liquid mist to the air ways.

Answer 50

Nabulizer/ Atomizer

Question 51

It pumps air or oxygen through a liquid medicine to turn it into a vapor, which is then inhaled by the patient.

Answer 51

Nebulizer/ Atomizer

Question 52

Atomizer/ Nebulizer Generally prefer to inhalers for patients, due to advantages such as:

Answer 52

1. Cheaper 2. More portable 3. Less-risk of side effects

Question 53

Only reserved for serious cases of respiratory sidease or severe attack

Answer 53

Nebulizer/ Atomizer

Question 54

Atomizer vs Nebulizer

Answer 54

Atomizer: Form of air particles Nebulizer: Form of mist