Preterm birth

Question 1

Prior PTB < 34w, CL < 25 mm before 24w, cerclage was assoc w/ what percent reduction in PTB < 35w?

Answer 1

30% reduction, 36% reduction in composite perinatal M&M
(based on pooled results of 5 clinical trials)

Question 2

Efficacy of vaginal P in women without prior PTB and CL <20 mm before 25w

Answer 2

44% decrease in PTB < 34w

Question 3

Efficacy of cerclage in women without prior PTB and CL < 25 mm btw 16 & 24w

Answer 3

Not associated with significant reduction in PTB < 35w (RR 0.76, 95% CI 0.52-1.15)