Primary biliary cholangitis

Question 1

typically seen in which patients?

Answer 1

middle aged females

9:1 ratio

Question 2

what antibody test do you do in PBC?

what immunoglobins rise in PBC?

Answer 2

AMA - anti-microbial antibodies

IgM

Question 3

classic patient presents as?

Answer 3

middle aged woman itching

cholestatic jaundice

Question 4

PBC - 80% are associated with what condition?

Answer 4

Sjrogen’s syndrome

Question 5

what happens to bloods?

therefore why d you do a US?

Answer 5

looks like cholestatic jaundice
^ALP
^gGT
^bilirubin

to exclude extrahepatic cholestasis

Question 6

what is PBC?

Answer 6

interlobular bile ducts become damaged