What are the three zones of the prostate
Peripheral, central, transitional
What is the largest zone of the prostate and most associated with prostate cancer?
Peripheral zone
BPH occurs in which zone?
Transitional
Only the ___ cells become neoplastic
secretory
BPH is the most common non-cancerous cause of __
PSA
___ men have a higher rate and more aggressive prostate cancer
Black
Invasive cancer loses the __ layer of cells
basal
A tumor volume of less than __ CC indicates a very low risk of progressoin
0.5
Staging T1a T1b T1c T2a T2b T2c T3a T3b T4
5% Only seen in needle biopsy 50% of one lobe Both Lobes Spread to extraprostatic tissue spread to seminal vesicle Metastasis
Gleason Grading 1 & 2 3 4 5
well formed glands
irregular gland infiltration
Cribriform plates
Cell sheets without any gland formation