Prothrombin Time (PT)

Question 1

Prothrombin time is also known as

Answer 1

Quick’s test

Question 2

The use of thromboplastin together with calcium chloride ACTIVATES THE EXTRINSIC PATHWAY OF COAGUALTION which leads to the formation of a CLOT.

Answer 2

Prothrombin Time (PT)

Question 3

Useful for MONITORING OF ANTICOAGULANT THERAPY (oral anticoagulant therapy)

Answer 3

Prothrombin Time (PT)

Question 4

Assess deficiency in extrinsic and common pathways (Factors VII, X, V, II, and I)

Answer 4

Prothrombin Time (PT)

Question 5

Useful too to ASSESS LIVER FUNCTION.

Answer 5

Prothrombin Time (PT)

Question 6

Specimen:

Answer 6

Citrated PPP

Question 7

Prothrombin time reagent:

Answer 7

Simplastin (Thromboplastin + 0.025 M CaCl2) - activates factor VII

Question 8

Procedure:

1. Pre-warm PLASMA at __ for a minimum of __ and a maximum of __.

Answer 8

• 37°C
• 2 minutes
• 10 minutes

Question 9

Procedure:

2. Pre- warm THROMBOPLASTIN at __ for a minimum of 2 minutes and a maximum of __.

Answer 9

• 37°C
• 60 minutes

Question 10

Reference range:

Answer 10

10 - 16 seconds

Question 11

It is recommended for use with patients undergoing anti coagulation therapy.

Answer 11

INR

Question 12

Transcribe ISI:

Answer 12

International Sensitivity Index

Question 13

A CALIBRATION PARAMETER that defines the responsiveness of the reagent relative to a WHO International Reference Preparation.

Answer 13

International Sensitivity Index (ISI)

Question 14

According to WHO the standard is __ when BUYING PT reagent.

Answer 14

1.0

Question 15

Lower sensitivity:

Answer 15

> 1.0

Question 16

High sensitivity:

Answer 16

< 1.0

Question 17

Transcribe INR

Answer 17

International Normalized Ratio

Question 18

STANDARDIZED report of PT (minimize difference in PT results)

Answer 18

International Normalized Ratio (INR)

Question 19

A mathematical calculation that CORRECTS FOR THE VARIABILITY IN in PT results caused by variable sensitivities (ISI) of thromboplastin agents used by laboratories.

Answer 19

International Normalized Ratio (INR)

Question 20

Used to: monitor patients taking oral anticoagulant therapy

Answer 20

International Normalized Ratio (INR)

Question 21

Treatment/prophylaxis for DVT:

[INR recommendations]

Answer 21

2.0 - 3.0

Question 22

Patients with prosthetic heart valves:

Answer 22

2.5 - 3.5

Question 23

Pulmonary embolism treatment:

Answer 23

3.0

Question 24

Low-Moderate oral anticoagulant therapy:

Answer 24

2.0 - 3.0

Question 25

High intensity oral anticoagulant therapy:

Answer 25

2.5 - 3.5

Question 26

INR of normal persons:

Answer 26

1