Itch
Unpleasant, poorly localised, non-adapting sensation that provokes the desire to scratch
Chemical mediators
Histamine
PGE2
ACh
Serotonin
Causes
Pruritoceptive
Neuropathic
Neurogenic
Psychogenic
Pruritoceptive itch
Something in skin that triggers itch
Neuropathic itch
Damage to central or peripheral nerves causing itch
eg shingles
Neurogenic itch
No evident damage in CNS but itch caused by
eg: opiate effects on CNS
Psychogenic itch
Psychological causes with no CNS damage
Management of itch
Anti-itch treatments are non specific
Sedative anti-histamines
Emollients
Anti-deppressants